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7th arrondissement Guillotière (south) Jean Macé Gerland Undecided (0.4%), A central hub of national rail network Paris's six major railway stations (Gare du Nord Gare de l'Est Gare de Lyon Gare d'Austerlitz Gare Montparnasse Gare Saint-Lazare) minor one (Gare de Bercy) connected three networks TGV serving four high-speed rail lines normal speed Corail trains suburban rails (Transilien)Métro RER tramway. In recent years city has also experienced large growth service sector employment switch from light manufacturing cultural high-tech economy.[citation needed] Marseille region home thousands of companies 90% of which small medium enterprises with less than 500 employees.[full citation needed] Among most famous ones CMA CGM container-shipping giant Compagnie maritime d'expertises (Comex) world leader sub-sea engineering hydraulic systems Airbus Helicopters Airbus division Azur Promotel active real estate development company La Provence local daily newspaper RTM Marseille's public transport company Société Nationale Maritime Corse Méditerranée (SNCM) major operator passenger vehicle freight transportation Western Mediterranean urban operation Euroméditerranée has developed large offer of offices thus Marseille hosts one of main business district FranceMarseille home of three main technopoles Château-Gombert (technological innovations) Luminy (biotechnology) La Belle de Mai (17,000 sq.m of offices dedicated multimedia activities)Tourism attractions.

See also Transportation Marseille France one of biggest contributors European Space Agency which conceived Ariane rocket family launched from French GuianaSince Middle Ages France has been major contributor scientific technological achievement Around beginning of 11th century Pope Sylvester II born Gerbert d'Aurillac reintroduced abacus armillary sphere introduced Arabic numerals clocks Northern Western EuropeUniversity of Paris founded mid-12th century still one of most important universities Western world 17th century mathematician René Descartes defined method acquisition of scientific knowledge while Blaise Pascal became famous his work probability fluid mechanics They were both key figures of Scientific revolution which blossomed Europe during this period Academy of Sciences was founded Louis XIV encourage protect spirit of French scientific research was forefront of scientific developments Europe 17th 18th centuries one of earliest academies of sciencesThe Age of Enlightenment was marked work of biologist Buffon chemist Lavoisier who discovered role of oxygen combustion while Diderot D'Alembert published Encyclopédie which aimed give access useful knowledge people knowledge that they can apply their everyday life With Industrial Revolution 19th century saw spectacular scientific developments France with scientists such Augustin Fresnel founder of modern optics Sadi Carnot who laid foundations of thermodynamics Louis Pasteur pioneer of microbiology Other eminent French scientists of 19th century have their names inscribed Eiffel TowerFamous French scientists of 20th century include mathematician physicist Henri Poincaré physicists Henri Becquerel Pierre Marie Curie remained famous their work radioactivity physicist Paul Langevin virologist Luc Montagnier co-discoverer of HIV AIDS Hand transplantation was developed 23 September 1998 Lyon team assembled from different countries around world including Jean-Michel Dubernard who shortly thereafter performed first successful double hand transplant Telesurgery was developed Jacques Marescaux his team 7 September 2001 across Atlantic Ocean (New-York-Strasbourg Lindbergh Operation)face transplant was first done 27 November 2005 Dr Bernard DevauchelleTop view of ring of European Synchrotron Radiation Facility, Notre-Dame de Reims Roman Catholic cathedral where kings of France were crowned until 1825.[XV], Maison Carrée temple Nemausus Corinthian columns portico. SeaMediterranean [icon] Basilica of Notre-Dame de Fourvière large 19th-century basilica top of Fourvière Hill, Ambox current red.svg The Stade Vélodrome home of Olympique de Marseille. The Élysée Palace residence of French President, The first book printed France Epistolae (Letters) Gasparinus de Bergamo (Gasparino da Barzizza) was published Paris 1470 press established Johann Heynlin Since then Paris has been centre of French publishing industry home of some of world's best-known writers poets setting many classic works of French literature Almost all books published Paris Middle Ages were Latin rather than French Paris did not become acknowledged capital of French literature until 17th century with authors such Boileau Corneille La Fontaine Molière Racine several coming from provinces foundation of Académie française 18th century literary life of Paris revolved around cafés salons was dominated Voltaire Jean-Jacques Rousseau Pierre de Marivaux BeaumarchaisDuring 19th century Paris was home subject some of France's greatest writers including Charles Baudelaire Stéphane Mallarmé Mérimée Alfred de Musset Marcel Proust Émile Zola Alexandre Dumas Gustave Flaubert Guy de Maupassant Honoré de Balzac Victor Hugo's Hunchback of Notre Dame inspired renovation of its setting Notre-Dame de Paris Another of Victor Hugo's works Les Misérables written while he was exile outside France during Second Empire described social change political turmoil Paris early 1830s One of most popular of all French writers Jules Verne worked Theatre Lyrique Paris stock exchange while he did research his stories National Library.[citation not found]. A Palme d'Or from Cannes Film Festival one of Big Three film festivals alongside Venice Film Festival Berlin International Film FestivalFrance has historical strong links with cinema with two Frenchmen Auguste Louis Lumière (known Lumière Brothers) having created cinema 1895 Several important cinematic movements including late 1950s 1960s Nouvelle Vague began country noted having strong film industry due part protections afforded French government France remains leader filmmaking of 2015 producing more films than any other European countrynation also hosts Cannes Festival one of most important famous film festivals worldApart from its strong innovative film tradition France has also been gathering spot artists from across Europe world this reason French cinema sometimes intertwined with cinema of foreign nations Directors from nations such Poland (Roman Polanski Krzysztof Kieślowski Andrzej Żuławski) Argentina (Gaspar Noé Edgardo Cozarinsky) Russia (Alexandre Alexeieff Anatole Litvak) Austria (Michael Haneke) Georgia (Géla Babluani Otar Iosseliani) prominent ranks of French cinema Conversely French directors have had prolific influential careers other countries such Luc Besson Jacques Tourneur or Francis Veber United StatesAlthough French film market dominated Hollywood France only nation world where American films make up smallest share of total film revenues 50% compared with 77% Germany 69% Japan French films account 35% of total film revenues of France which highest percentage of national film revenues developed world outside United States compared 14% Spain 8% UK France 2013 2nd exporter of films world after United StatesUntil recently France had centuries been cultural center of world, although its dominant position has been surpassed United States Subsequently France takes steps protecting promoting its culture becoming leading advocate of cultural exceptionnation succeeded convincing all EU members refuse include culture audiovisuals list of liberalised sectors of WTO 1993 Moreover this decision was confirmed voting UNESCO 2005 principle of cultural exception won overwhelming victory 198 countries voted it only 2 countries U.S Israel voted against itFashion.