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Paris has been international capital of high fashion since 19th century particularly domain of haute couture clothing hand-made order private clients home of some of largest fashion houses world including Dior Chanel of many well-known fashion designers including Karl Lagerfeld Jean-Paul Gaultier Christophe Josse Christian Lacroix Paris Fashion Week held January July Carrousel du Louvre other city locations among top four events of international fashion calendar along with fashion weeks Milan London New York Paris also home of world's largest cosmetics company L'Oréal three of five top global makers of luxury fashion accessories Louis Vuitton Hermés Cartier Most of major fashion designers have their showrooms along Avenue Montaigne between Champs-Élysées SeineHolidays festivals, The GDP of Lyon was 74 billion euro 2012, it's second richest city France after Paris Lyon its region Rhône-Alpes represent one of most important economies Europe and according Loughborough University can be compared Philadelphia Mumbai or Athens with regard its international position city of Lyon working partnership more easily enable establishment of new headquarters territory (ADERLY Chambre du commerce et d'industrie Grand Lyon...) High-tech industries such biotechnology software development video game (Arkane Studios Ivory Tower Eden Games EA France Bandai Namco Entertainment Europe) internet services also growing Other important sectors include medical research technology non-profit institutions universities Lyon home P4-Inserm–ean Merieux Laboratory which conducts top-level vaccine researchThe city home headquarters of many large companies such Groupe SEB Sanofi Pasteur Renault Trucks Norbert Dentressangle LCL S.ADescours & Cabaud Merial Point S BioMérieux Iveco Bus Compagnie Nationale du Rhône GL Events April Group Boiron Feu Vert Panzani Babolat Euronews Lyon Airports LVL Medical inter-governmental agencies IARC Interpol specialisation of some sectors of activities has led creation of many main business centres La Part-Dieu located 3rd arrondissement second biggest business quarter after La Défense Paris with over 1,600,000 m2 (17,222,256.67 sq ft) of office space services more than 55,000 jobs Cité Internationale created architect Renzo Piano located border of Parc de la Tête d'Or 6th arrondissement worldwide headquarters of Interpol located there district of Confluence south of historic centre new pole of economical cultural developmentTourism important part of Lyon economy with one billion euros 2007 3.5 million hotel-nights 2006 provided non-residents Approximately 60% of tourists visit business with rest leisure January 2009 Lyon ranked first France hostels business festivals most important attracting tourists Fête des lumières Nuits de Fourvière every summer Biennale d'art contemporain Nuits SonoresDemographics, Main article Culture of France See also Taxation France. Camille Pissarro Boulevard Montmartre 1897 Hermitage Museum They take place three main sites Palais du Pharo Palais des Congrès et des Expositions (Parc Chanot) World Trade Center2012 Marseille hosted World Water Forum Several urban projects have been developed make Marseille attractive Thus new parks museums public spaces real estate projects aim improve city's quality of life (Parc du 26e Centenaire Old Port of Marseille, numerous places Euroméditerranée) attract firms people Marseille municipality acts develop Marseille regional nexus entertainment south of France with high concentration of museums cinemas theatres clubs bars restaurants fashion shops hotels art galleriesEmployment!