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The main French research bodies including CNRS INSERM INRA all well represented Marseille Scientific research concentrated several sites across city including Luminy where there institutes developmental biology (the IBDML) immunology (CIML) marine sciences neurobiology (INMED) CNRS Joseph Aiguier campus (a world-renowned institute of molecular environmental microbiology) Timone hospital site (known work medical microbiology) Marseille also home headquarters of IRD which promotes research into questions affecting developing countriesTransport, By 1901 population of Paris had grown 2,715,000 beginning of century artists from around world including Pablo Picasso Modigliani Henri Matisse made Paris their home was birthplace of Fauvism Cubism abstract art, authors such Marcel Proust were exploring new approaches literatureDuring First World War Paris sometimes found itself front line 600 1,000 Paris taxis played small but highly important symbolic role transporting 6,000 soldiers front line First Battle of Marne city was also bombed Zeppelins shelled German long-range guns years after war known Les Années Folles Paris continued be mecca writers musicians artists from around world including Ernest Hemingway Igor Stravinsky James Joyce Josephine Baker Sidney Bechet surrealist Salvador DalíIn years after peace conference city was also home growing numbers of students activists from French colonies other Asian African countries who later became leaders of their countries such Ho Chi Minh Zhou Enlai Léopold Sédar SenghorGeneral Charles de Gaulle Champs-Élysées celebrating liberation of Paris (26 August 1944), See also List of French monarchs France Middle Ages. 5th arrondissement Vieux Lyon (Saint-Paul Saint-Jean Saint-Georges) Saint-Just Saint-Irénée, Fourvière Point du Jour Ménival Battières Champvert (south) The Rhône Saône converge south of historic city centre forming peninsula – Presqu'île – bounded two large hills west north large plain eastward Place Bellecour located Presqu'île between two rivers third-largest public square France broad pedestrian-only Rue de la République leads north from Place BellecourThe northern hill La Croix-Rousse known the hill that works because traditionally home many small silk workshops industry which city has long been renownedThe western hill Fourvière known the hill that prays because location basilica of Notre-Dame de Fourvière several convents residence of Archbishop district Vieux Lyon also hosts Tour métallique (a highly visible TV tower replicating last stage of Eiffel Tower) one of city's funicular railways Fourvière along with portions of Presqu'île much of La Croix-Rousse designated UNESCO World Heritage siteEast of Rhône from Presqu'île large flat area upon which sits much of modern Lyon contains most of city's population Situated this area urban centre of La Part-Dieu which clusters landmark structures Tour Part-Dieu Tour Oxygène Tour Swiss Life well city's primary railway station Gare de Lyon-Part-DieuNorth of this district sixth arrondissement which home one of Europe's largest urban parks Parc de la Tête d'or well Lycée du Parc Interpol's world headquartersPanorama of city of Lyon. In 2017 Paris-Charles de Gaulle Airport was second-busiest airport Europe tenth-busiest airport worldParis major international air transport hub with 5th busiest airport system world city served three commercial international airports Paris-Charles de Gaulle Paris-Orly Beauvais-Tillé Together these three airports recorded traffic of 96.5 million passengers 2014 There also one general aviation airport Paris-Le Bourget historically oldest Parisian airport closest city centre which now used only private business flights air showsOrly Airport located southern suburbs of Paris replaced Le Bourget principal airport of Paris from 1950s 1980s Charles de Gaulle Airport located edge of northern suburbs of Paris opened commercial traffic 1974 became busiest Parisian airport 1993 year 2017 was 5th busiest airport world international traffic hub nation's flag carrier Air France Beauvais-Tillé Airport located 69 kilometres (43 miles) north of Paris's city centre used charter airlines low-cost carriers such RyanairDomestically air travel between Paris some of France's largest cities such Lyon Marseille or Strasbourg has been large measure replaced high-speed rail due opening of several high-speed TGV rail lines from 1980s example after LGV Méditerranée opened 2001 air traffic between Paris Marseille declined from 2,976,793 passengers 2000 1,502,196 passengers 2014 After LGV Est opened 2007 air traffic between Paris Strasbourg declined from 1,006,327 passengers 2006 157,207 passengers 2014Internationally air traffic has increased markedly recent years between Paris Gulf airports emerging nations of Africa Russia Turkey Portugal Italy mainland China whereas noticeable decline has been recorded between Paris British Isles Egypt Tunisia JapanMotorways. The Paris Métro busiest subway network European UnionSince inauguration of its first line 1900 Paris's Métro (subway) network has grown become city's most widely used local transport system today carries about 5.23 million passengers daily through 16 lines 303 stations (385 stops) 220 km (136.7 mi) of rails Superimposed this 'regional express network' RER whose five lines (A B C D E) 257 stops 587 km (365 mi) of rails connect Paris more distant parts of urban areaOver €26.5 billion will be invested over next 15 years extend Métro network into suburbs, with notably Grand Paris Express projectIn addition Paris region served light rail network of nine lines tramway Line T1 runs from Asnières-Gennevilliers Noisy-le-Sec Line T2 runs from Pont de Bezons Porte de Versailles Line T3a runs from Pont du Garigliano Porte de Vincennes Line T3b runs from Porte de Vincennes Porte de la Chapelle Line T5 runs from Saint-Denis Garges-Sarcelles Line T6 runs from Châtillon Viroflay Line T7 runs from Villejuif Athis-Mons Line T8 runs from Saint-Denis Épinay-sur-Seine Villetaneuse all of which operated RATP Group, line T4 runs from Bondy RER Aulnay-sous-Bois which operated state rail carrier SNCF Five new light rail lines currently various stages of developmentAir; Musée Gadagne museum of history of Lyon housed historic building Vieux Lyon Also includes large collection of marionnettes! Châteaux Université Paul Cézanne Aix-Marseille III, France one of biggest contributors European Space Agency which conceived Ariane rocket family launched from French GuianaSince Middle Ages France has been major contributor scientific technological achievement Around beginning of 11th century Pope Sylvester II born Gerbert d'Aurillac reintroduced abacus armillary sphere introduced Arabic numerals clocks Northern Western EuropeUniversity of Paris founded mid-12th century still one of most important universities Western world 17th century mathematician René Descartes defined method acquisition of scientific knowledge while Blaise Pascal became famous his work probability fluid mechanics They were both key figures of Scientific revolution which blossomed Europe during this period Academy of Sciences was founded Louis XIV encourage protect spirit of French scientific research was forefront of scientific developments Europe 17th 18th centuries one of earliest academies of sciencesThe Age of Enlightenment was marked work of biologist Buffon chemist Lavoisier who discovered role of oxygen combustion while Diderot D'Alembert published Encyclopédie which aimed give access useful knowledge people knowledge that they can apply their everyday life With Industrial Revolution 19th century saw spectacular scientific developments France with scientists such Augustin Fresnel founder of modern optics Sadi Carnot who laid foundations of thermodynamics Louis Pasteur pioneer of microbiology Other eminent French scientists of 19th century have their names inscribed Eiffel TowerFamous French scientists of 20th century include mathematician physicist Henri Poincaré physicists Henri Becquerel Pierre Marie Curie remained famous their work radioactivity physicist Paul Langevin virologist Luc Montagnier co-discoverer of HIV AIDS Hand transplantation was developed 23 September 1998 Lyon team assembled from different countries around world including Jean-Michel Dubernard who shortly thereafter performed first successful double hand transplant Telesurgery was developed Jacques Marescaux his team 7 September 2001 across Atlantic Ocean (New-York-Strasbourg Lindbergh Operation)face transplant was first done 27 November 2005 Dr Bernard DevauchelleTop view of ring of European Synchrotron Radiation Facility. Tourists from around world make Louvre most-visited art museum worldGreater Paris comprising Paris its three surrounding departments received 23.6 million visitors 2017 measured hotel arrivals These included 12 million foreign visitors 11.5 million French visitors Of foreign visitors greatest number came from United States (2 million) Great Britain (1.1 million) Germany (802.6 thousand) China (774.4 thousand)In 2016 measured MasterCard Global Cities Destination Index Paris was third-busiest airline destination world with 18.03 million visitors behind Bangkok (21.47 million) London (19.88 million) According Paris Convention Visitors Bureau 393,008 workers Greater Paris or 12.4% of total workforce engaged tourism-related sectors such hotels catering transport leisureMonuments attractions, The Gare du Nord railway station busiest EuropeParis major rail highway air transport hub Île-de-France Mobilités formerly Syndicat des transports d'Île-de-France (STIF) before that theSyndicat des transports parisiens (STP) oversees transit network regionsyndicate coordinates public transport contracts out RATP (operating 347 bus lines Métro eight tramway lines sections of RER) SNCF (operating suburban rails one tramway line other sections of RER) Optile consortium of private operators managing 1,176 bus linesRailways. Main article Lutetia Climate Université Lumière (Lyon 2) Health care emergency medical service city of Paris its suburbs provided Assistance publique – Hôpitaux de Paris (AP-HP) public hospital system that employs more than 90,000 people (including practitioners support personnel administrators) 44 hospitalslargest hospital system Europe provides health care teaching research prevention education emergency medical service 52 branches of medicine hospitals receive more than 5.8 million annual patient visitsOne of most notable hospitals Hôtel-Dieu founded 651 oldest hospital city Other hospitals include Pitié-Salpêtrière Hospital (one of largest Europe) Hôpital Cochin Hôpital Bichat Hôpital Européen Georges-Pompidou Bicêtre Hospital Beaujon Hospital Curie Institute Lariboisière Hospital Necker-Enfants Malades Hospital Hôpital Saint-Louis Hôpital de la Charité American Hospital of ParisMedia.

The Hôtel-Dieu de Paris oldest hospital city ENTPE (École Nationale des Travaux Publiques de l'État) Parc Olympique Lyonnais. See also Marseille-Fos Port The population of Paris today lower than its historical peak of 2.9 million 1921 principal reasons were significant decline household size dramatic migration of residents suburbs between 1962 1975 Factors migration included de-industrialisation high rent gentrification of many inner quarters transformation of living space into offices greater affluence among working families city's population loss came end 21st century population estimate of July 2004 showed population increase first time since 1954 population reached 2,234,000 2009According Eurostat EU statistical agency 2012 Commune of Paris was most densely populated city European Union with 21,616 people per square kilometre within city limits (the NUTS-3 statistical area) ahead of Inner London West which had 10,374 people per square kilometre According same census three departments bordering Paris Hauts-de-Seine Seine-Saint-Denis Val-de-Marne had population densities of over 10,000 people per square kilometre ranking among 10 most densely populated areas of EUMigration.